Michael R Freeman Selected Research

MAP Kinase Kinase 7

1/2022

Receptor-interacting protein kinase 2 (RIPK2) stabilizes c-Myc and is a therapeutic target in prostate cancer metastasis.

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Michael R Freeman Research Topics

Disease

69	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 04/2002
56	Neoplasms (Cancer) 01/2022 - 04/2002
14	Neoplasm Metastasis (Metastasis) 01/2022 - 08/2007
9	Interstitial Cystitis (Interstitial Cystitis, Chronic) 01/2015 - 08/2007
7	Urinary Bladder Neoplasms (Bladder Cancer) 08/2015 - 01/2003
6	Hypercholesterolemia 09/2012 - 07/2006
6	Carcinoma (Carcinomatosis) 08/2012 - 12/2002
5	Breast Neoplasms (Breast Cancer) 01/2019 - 06/2003
5	Disease Progression 11/2018 - 01/2003
4	Adenocarcinoma 01/2022 - 01/2012
3	Coronary Artery Disease (Coronary Atherosclerosis) 01/2020 - 10/2003
3	Inflammation (Inflammations) 01/2019 - 07/2008
3	Circulating Neoplastic Cells 01/2019 - 01/2016
3	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 10/2010 - 01/2003
3	Hyperplasia 09/2010 - 05/2002
3	Transitional Cell Carcinoma 03/2006 - 01/2003
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 01/2012
2	Acute Coronary Syndrome 01/2020 - 01/2019
2	Atherosclerosis 01/2020 - 06/2007
2	Pain (Aches) 01/2015 - 01/2012
2	Carcinogenesis 01/2012 - 10/2007
2	Hypertrophy 12/2006 - 05/2002
1	Chromosomal Instability (Chromosome Stability) 05/2020

Drug/Important Bio-Agent (IBA)

29	CholesterolIBA 01/2022 - 04/2002
26	Proteins (Proteins, Gene)FDA Link 01/2022 - 05/2002
14	Androgen Receptors (Androgen Receptor)IBA 01/2021 - 12/2002
14	LipidsIBA 01/2020 - 04/2002
12	AndrogensIBA 01/2021 - 12/2002
11	Biomarkers (Surrogate Marker)IBA 06/2020 - 06/2003
8	ErbB Receptors (EGF Receptor)IBA 01/2020 - 11/2004
7	Phosphotransferases (Kinase)IBA 01/2022 - 11/2004
7	Messenger RNA (mRNA)IBA 01/2020 - 12/2002
7	Hormones (Hormone)IBA 01/2018 - 01/2004
7	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 04/2014 - 12/2002
5	Pharmaceutical PreparationsIBA 01/2022 - 03/2006
5	Ezetimibe (Zetia)FDA Link 01/2022 - 03/2009
5	Transcription Factors (Transcription Factor)IBA 01/2021 - 01/2013
5	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 12/2018 - 06/2006
5	Caveolin 1IBA 09/2013 - 08/2007
5	Epidermal Growth Factor (EGF)IBA 02/2009 - 04/2002
4	RNA (Ribonucleic Acid)IBA 05/2020 - 11/2012
4	Peptides (Polypeptides)IBA 01/2020 - 12/2002
4	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 06/2011 - 04/2002
4	Heparin (Liquaemin)FDA LinkGeneric 02/2009 - 12/2002
4	Heparin-binding EGF-like Growth Factor (HB-EGF)IBA 02/2009 - 04/2005
3	Prostate-Specific Antigen (Semenogelase)IBA 01/2021 - 04/2004
3	LigandsIBA 12/2016 - 10/2007
3	ElementsIBA 01/2013 - 04/2004
3	SialoglycoproteinsIBA 01/2012 - 08/2007
3	Tyrosine (L-Tyrosine)FDA Link 07/2009 - 04/2005
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 07/2008 - 09/2005
2	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2022 - 03/2021
2	olaparibIBA 01/2022 - 01/2021
2	CytokinesIBA 01/2021 - 02/2004
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2021 - 01/2013
2	Phenobarbital (Luminal)FDA Link 01/2021 - 01/2016
2	AutoantigensIBA 01/2020 - 01/2019
2	27-hydroxycholesterolIBA 01/2020 - 01/2017
2	Keratin-8 (Keratin 8)IBA 01/2019 - 06/2003
2	ForminsIBA 11/2018 - 07/2009
2	DNA (Deoxyribonucleic Acid)IBA 01/2018 - 05/2002
2	LDL Receptors (LDL Receptor)IBA 01/2017 - 01/2017
2	Ubiquitin-Specific ProteasesIBA 08/2015 - 03/2012
2	Deubiquitinating EnzymesIBA 08/2015 - 03/2012
2	Amino Acids FDA Link 05/2015 - 06/2011
2	Glutamine (L-Glutamine)FDA Link 05/2015 - 12/2011
2	EnzymesIBA 05/2015 - 01/2012
2	Small Interfering RNA (siRNA)IBA 09/2013 - 09/2010
2	Fatty Acid Synthases (Fatty Acid Synthase)IBA 01/2013 - 08/2007
2	Metalloproteases (Metalloproteinases)IBA 11/2012 - 09/2005
2	GlycopeptidesIBA 12/2011 - 01/2011
2	CalciumIBA 09/2010 - 12/2002
2	p38 Mitogen-Activated Protein KinasesIBA 02/2009 - 06/2007
2	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 07/2008 - 09/2005
2	Interleukin-6 (Interleukin 6)IBA 02/2007 - 02/2004
2	MitogensIBA 12/2006 - 12/2002
2	NF-kappa B (NF-kB)IBA 11/2006 - 04/2004
2	CaveolinsIBA 02/2004 - 04/2002
1	MAP Kinase Kinase 7IBA 01/2022
1	Protein Kinases (Protein Kinase)IBA 01/2022
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2022
1	Mechanistic Target of Rapamycin Complex 2IBA 01/2022
1	N- (oxo- 5,6- dihydrophenanthridin- 2- yl)- N,N- dimethylacetamide hydrochlorideIBA 03/2021
1	AntioxidantsIBA 03/2021
1	protein acyltransferaseIBA 03/2021
1	Ribose (D-Ribose)IBA 01/2021
1	Nuclear Matrix-Associated ProteinsIBA 01/2021
1	Bovine Serum AlbuminIBA 01/2021
1	Co-Repressor ProteinsIBA 01/2021
1	ProteomeIBA 06/2020
1	Indicators and Reagents (Reagents)IBA 05/2020
1	Apolipoproteins E (ApoE)IBA 01/2020
1	epidermal growth factor receptor VIIIIBA 01/2020
1	AntigensIBA 01/2020

Therapy/Procedure

17	Therapeutics 01/2022 - 11/2004
11	Castration 01/2021 - 12/2011
2	Prostatectomy (Retropubic Prostatectomy) 01/2022 - 01/2020
2	Drug Therapy (Chemotherapy) 07/2015 - 03/2012
2	Intravesical Administration 07/2008 - 03/2006
1	Chemoprevention 01/2022